Letter Re: So-Called Totally Drug-Resistant Tuberculosis in South Africa
Sir: Regarding your recent link to the US News article: “Doctors Struggling to Fight ‘Totally Drug-Resistant’ Tuberculosis in South Africa”, I would like to comment. As an infectious diseases research scientist with a specialty in tuberculosis (TB) the term “Totally Drug Resistant” peaked my interest, considering the World Health Organization (WHO) does not recognize this term. To express the resistance to anti-TB drugs, we use very precise terms, where multidrug resistance (MDR-) represents resistance to two specific drugs, isoniazid and rifampin, and extensively-drug resistance (XDR-) is resistance to any of the second line drugs and one of the injectable …