James:
Re: the assertion: “Two weeks after the expiration date, these agents can and frequently do become nephrotoxic” No, they always are nephrotoxic – it is dose related. The above statement is just plain wrong. Mis-dosing causes renal failure – which is an equally valid concern for do it yourselfers using vet abs – but not the d**n expiry date – I thought we had put the tetracycline debate to rest – in the 80’s it composition was unstable – it broke down 6-12 months post-expiry date and became potentially toxic from the degradation products of the binder. Since late-1980s, The new binder has meant less problem. Although vet abs remain potentially dangerous for many reasons – but not due to degradation within two weeks of the expiry dates. – A Doctor in New Zealand
Two Letters Re: Veterinary Antibiotics
